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Diagnosis in patients with hyperoxaluria, recurrent kidney stones and/or nephrocalcinosis.

In collaboration with the Wisplinghoff lab we are able to determine both lithogenic (e.g. oxalate, calcium), as well as stone inhibitory substances (e.g. citrate) in urine, but also in plasma samples.

For better diagnostic evaluation of patients with primary hyperoxaluria we additionally offer analysis of glycolate (PH I), as well as L-glyceric acid (PH II) and hydroxy-oxo-glutrate (PH III), dihydroxy-glutarate (DHG) and 4-hydroxy-ketoglutamate (4OHGlu)in both urine and plasma samples. For research purposes we also measure glyoxylate.

Ideally, one or better two-three 24 h urines should be collected and send for analysis. Spot urine samples can be obtained in infants and small children.

Please adhere to the preservation rules and the specific mailing information on our lab sheets.


Contact us


Deutsches Hyperoxaluriezentrum, c/o Kindernierenzentrum Bonn, Dr. Gesa Schalk & Prof. Dr. Bernd Hoppe, Im Mühlenbach 2b, 53127 Bonn

+49 (0)228 6883860